![]() It protects your baby’s red blood cells from attack if her blood comes into contact with yours during labor and delivery and helps prevent Rh-related complications from happening in later pregnancies. Getting a RhoGAM shot is the best way to prevent any possible complications from Rh incompatibility. If you test Rh negative and the baby’s father subsequently tests Rh positive, your doctor will recommend that you get the RhoGAM shot. If you test Rh positive, the shot isn't necessary. Do I need the RhoGAM shot during pregnancy? Like other shots, RhoGAM is injected into your arm or backside. In other words, it keeps you and your baby’s Rh incompatibility from causing any possible problems should your blood types mix at any point during your pregnancy or delivery. The shot contains antibodies (collected from plasma donors) that stop your immune system from reacting to your baby’s Rh positive blood cells. ![]() RhoGAM is the injection used to prevent Rh incompatibility from developing during pregnancy. The good news is that Rh incompatibility is easy to treat with a RhoGAM shot. That’s why your doctor will test your Rh factor early on in pregnancy. This can lead to potential complications (especially if you become pregnant with another Rh positive baby in the future) because your immune system will mount an attack against those Rh positive red blood cells. Trusted Source KidsHealth From Nemours Rh Incompatibility During Pregnancy See All Sources If your baby’s blood comes into contact with yours during pregnancy or delivery, your body can build antibodies against the Rh factor. Rh incompatibility happens when an expecting mom is Rh negative and her baby is Rh positive. Whether you’re Rh positive or negative doesn’t matter much, except when it comes to pregnancy. O+ blood, for instance, has the Rh factor, while O- blood does not. This symbol indicates whether or not the Rh factor is in your bloodstream. If you’ve ever gotten a blood test or given blood, you probably noticed the “+” or “–” at the end of your blood type. Trusted Source Merck Manual Hemolytic Disease of the Fetus and Newborn See All Sources Negative Rh factor occurs in about 15 percent of white people, between 4 and 8 percent of Black people and 0.3 percent of Asian people. Trusted Source American College of Obstetricians and Gynecologists The Rh Factor: How It Can Affect Your Pregnancy See All Sources ![]() If you carry the protein, you’re Rh positive. Rh factor is a type of protein often found on the surface of red blood cells, which carry oxygen throughout the body. ![]()
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